Hemodynamics Primary heart data, originating from 100 Gttingen minipigs of 20 kg. *1)
| heart rate (BPM) |
103 /- 14 |
| systolic blood pressure (mmHg) |
148 /- 15 |
| diastolic blood pressure (mmHg) |
96 /-14 |
| MAP (mmHg) |
118 /- 14 |
| HMV (ml/min) |
3147 /- 271 |
| stroke volume (ml) |
24.7 |
| left ventricle pressue, systolic (mmHg) |
142 /- 14 |
| left ventricle pressure, diastolic (mmHg) |
7 /- 2 |
| end diastolic pressure (mmHg) |
18 /- 3 |
Heart data recorded from 7 Gttingen Minipigs (22-32 kg) fitted with radiotelemetry transmiters. *2)
| heart rate (BPM) |
56 /- 7 |
| systolic blood pressure (mmHg) |
122 /- 15 |
| diastolic blood pressure (mmHg) |
86 /-10 |
| left ventricle pressue, systolic (mmHg) |
113 /- 15 |
Organ blood flow distribution, originating from 16 Gttingen minipigs of 3 kg (HMV= 717 /- 224 ml/min). *1)
|
% of HMV |
ml/100g tissue/min |
| heart |
4.5 |
118 /- 45 |
| brain |
5.1 |
76 /- 21 |
| esophagus |
0.1 |
16 /- 11 |
| stomach |
2.6 |
59 /- 44 |
| small intestine |
11.0 |
79 /- 49 |
| cecum |
1.1 |
96 /- 68 |
| large intestine |
3.4 |
43 /- 30 |
| pancreas |
1.4 |
147 /- 166 |
| spleen |
3.3 |
297 /- 232 |
| kidneys |
17.0 |
361 /- 86 |
| adrenals |
0.1 |
82 /- 62 |
| skin |
5.0 |
8 /- 4 |
| muscles |
- |
14 /- 6 |
| fat tissues |
- |
11 /- 6 |
| liver (total) |
26 |
167 /- 74 |
| liver (portal) |
23 |
- |
| GI tract (total) |
18 |
71 /- 46 |
References: Beglinger, R. and M. Becker, Herz und Kreislauf, In: P. Glodek and B. Oldigs (eds.), Das Gttinger Miniaturschwein, Paul Parey, Berlin, 1982, 75-85. *1) Stubhan, M., M. Markeert, K. Mayer, T. Trautmann, A. Klumpp, J. Henke, and B. Guth. Evaluation of cardiovascular and ECG parameters in the normal, freely moving Gttingen Minipig. Journal of Pharmacological and Toxicological Methods 57 (2008) 202-211 *2) |
